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De Novo Protein Sequencing

De Novo Protein Sequencing
Service Details
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Enzyme digestion

Hydrolyze monoclonal antibody proteins into short peptides by using multiple enzymes.

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Tandem mass spectrometry

Using a high-precision mass spectrometer to generate tandem mass spectrometry data.

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Short peptide de novo sequencing

Using PEAKS AB de novo sequencing algorithm decomposes tandem mass spectrometry data into short peptide sequences to obtain amino acid sequence information.

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Protein assembly

Assemble amino acid sequences using the de novo algorithm to obtain complete antibody protein sequences, and identify leucine and isoleucine one by one.

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Molecular weight verification

Verify whether the molecular weight of the assembled amino acid sequence is correct through antibody light and heavy chain molecular weight experiments.

Service Workflow
Alternate Text Customer Consultation
Alternate Text Program and contract confirmation
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Alternate Text Feedback and sample delivery
Alternate Text Scalable production
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